Guidance for Local Health Jurisdictions on Isolation and Quarantine of the General Public | Jan. 8, 2022

The Omicron variant, designated as a variant of concern, has been identified in California and a number of other states. The California Department of Public Health (CDPH) is monitoring genomic sequencing data as we seek to determine the impact of the Omicron variant and other variants on SARS-CoV-2 transmission and disease severity in California. Early data regarding the Omicron variant suggest the increased transmissibility of the Omicron variant is two to four times as infectious as the Delta variant, and there is evidence of immune evasion. Recent evidence also shows that vaccine effectiveness against COVID-19 infection is decreasing over time without boosters. There is still much to be learned about the Omicron variant, and it is important to remain vigilant at this time

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